Search results for "Motor speech"
showing 3 items of 3 documents
Narrowing the Genetic Causes of Language Dysfunction in the 1q21.1 Microduplication Syndrome
2018
The chromosome 1q21.1 duplication syndrome (OMIM# 612475) is characterized by head anomalies, mild facial dysmorphisms, and cognitive problems, including autistic features, mental retardation, developmental delay, and learning disabilities. Speech and language development are sometimes impaired, but no detailed characterization of language problems in this condition has been provided to date. We report in detail on the cognitive and language phenotype of a child who presents with a duplication in 1q21.1 (arr[hg19] 1q21.1q21.2(145,764,455-147,824,207) × 3), and who exhibits cognitive delay and behavioral disturbances. Language is significantly perturbed, being the expressive domain the most …
“Accent issue”: foreign accent syndrome following ischemic stroke
2019
Background: Foreign accent syndrome (FAS) is arare syndrome associated with altered speech rhythm and prosody, which listeners perceive as foreign; cerebrovascular accidents, tumors and multiple sclerosis are reported as possible causes of FAS. The pathophysiology of FAS is not yet understood. Case presentation: A 68-year-old Italian man was admitted to the EmergencyDepartment for non-fluent aphasia and dysarthria. Computed tomography (CT) scan did not show abnormalities; the patient was treated with systemic thrombolysis. A repeated brain CT and magnetic resonance imaging (MRI) confirmed an infarct in the left primary motor cortex and mild extension to cortico-subcortical frontal regions. …
A specific picture of speech disturbances in Polish speaking patients with mixed dysarthria in multiple sclerosis (MS) and in Wilson's disease (WD)
2014
The aim of this paper is to compare a specific picture of speech disturbances in Polish-speaking patients with mixed dysarthria in multiple sclerosis (MS), and in Wilson’s disease (WD). We selected for the experiment 20 persons with dysarthria of different origin: 10 persons with dysarthria in multiple sclerosis (MS), and 10 persons with dysarthria in Wilson’s disease (WD). The compared groups were similar in age and the severity of the dysarthria. Patients read 11 words containing selected Polish sounds distinguished according to the manner of articulation. The results were qualitatively and quantitatively analyzed (using a non-parametric Mann-Whitney U test). The picture of speech product…